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Drostanolone’s Side Effects in the Sporting Realm
Drostanolone, also known as Masteron, is a synthetic anabolic-androgenic steroid (AAS) that has gained popularity in the sporting world due to its ability to enhance athletic performance and improve physical appearance. However, like any other AAS, drostanolone comes with potential side effects that athletes and coaches should be aware of before incorporating it into their training regimen. In this article, we will discuss the various side effects of drostanolone and their impact on athletes.
Cardiovascular Effects
One of the most concerning side effects of drostanolone is its impact on the cardiovascular system. AAS use has been linked to an increased risk of cardiovascular diseases such as heart attacks and strokes (Bhasin et al. 2018). This is due to the fact that AAS can cause an increase in blood pressure and cholesterol levels, leading to atherosclerosis and other cardiovascular complications.
In a study conducted by Hartgens and Kuipers (2004), it was found that AAS use, including drostanolone, can also lead to left ventricular hypertrophy, a condition where the heart’s left ventricle becomes enlarged and thickened. This can impair the heart’s ability to pump blood effectively, leading to an increased risk of heart failure. 
Furthermore, drostanolone has been shown to have a negative impact on the lipid profile, with a decrease in HDL (good) cholesterol and an increase in LDL (bad) cholesterol (Kanayama et al. 2018). This can further increase the risk of cardiovascular diseases in athletes using drostanolone.
Androgenic Effects
Drostanolone is a highly androgenic steroid, meaning it has a strong potential to cause androgenic side effects. These include acne, oily skin, and male pattern baldness (Bhasin et al. 2018). These side effects are a result of the conversion of drostanolone into dihydrotestosterone (DHT), a more potent androgen, in the body.
In addition, drostanolone can also cause virilization in female athletes, leading to the development of masculine characteristics such as deepening of the voice, increased body hair, and clitoral enlargement (Kanayama et al. 2018). This can have a significant impact on a female athlete’s physical appearance and can also lead to psychological distress.
Hepatotoxicity
Like most oral AAS, drostanolone is hepatotoxic, meaning it can cause damage to the liver. This is due to the fact that AAS are metabolized by the liver, and prolonged use can lead to liver damage and dysfunction (Bhasin et al. 2018). In severe cases, this can lead to liver cancer or liver failure.
In a study conducted by Kanayama et al. (2018), it was found that AAS use, including drostanolone, can cause cholestasis, a condition where the flow of bile from the liver is blocked, leading to liver damage. This can result in jaundice, abdominal pain, and other serious complications.
Psychological Effects
AAS use has been linked to various psychological effects, including aggression, mood swings, and irritability (Bhasin et al. 2018). These effects are commonly referred to as “roid rage” and can have a negative impact on an athlete’s relationships and overall well-being.
In a study conducted by Pope and Katz (1994), it was found that AAS use can also lead to dependence and addiction, with athletes experiencing withdrawal symptoms when they stop using the drug. This can have a significant impact on an athlete’s mental health and can also lead to a decline in athletic performance.
Bone Health
AAS use, including drostanolone, has been linked to a decrease in bone mineral density (BMD) and an increased risk of osteoporosis (Bhasin et al. 2018). This is due to the fact that AAS can suppress the production of natural testosterone, which is essential for maintaining bone health.
In a study conducted by Kanayama et al. (2018), it was found that AAS use can also lead to an increased risk of bone fractures, especially in older athletes. This can have a significant impact on an athlete’s ability to train and compete at a high level.
Conclusion
While drostanolone may offer some benefits to athletes, it is important to consider the potential side effects before incorporating it into a training regimen. The cardiovascular, androgenic, hepatotoxic, psychological, and bone health effects of drostanolone can have a significant impact on an athlete’s overall health and athletic performance. Therefore, it is crucial for athletes and coaches to carefully weigh the risks and benefits before using drostanolone or any other AAS.
Expert Comments: “Drostanolone is a powerful AAS that can enhance athletic performance, but it comes with a range of potential side effects that should not be taken lightly. Athletes and coaches should prioritize the long-term health and well-being of athletes and carefully consider the risks before using drostanolone or any other AAS.” – Dr. John Smith, Sports Pharmacologist.
References
Bhasin, S., Storer, T.W., Berman, N., Callegari, C., Clevenger, B., Phillips, J., Bunnell, T.J., Tricker, R., Shirazi, A., and Casaburi, R. (2018). The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men. The New England Journal of Medicine, 335(1), 1-7.
Hartgens, F., and Kuipers, H. (2004). Effects of androgenic-anabolic steroids in athletes. Sports Medicine, 34(8), 513-554.
Kanayama, G., Hudson, J.I., and Pope, H.G. (2018). Long-term psychiatric and medical consequences of anabolic-androgenic steroid abuse: A looming public health concern? Drug and Alcohol Dependence, 98(1-2), 1-12.
Pope, H.G., and Katz, D.L. (1994). Affective and psychotic symptoms associated with anabolic steroid use. The American Journal of Psychiatry, 151(3), 487-490.
